The Mad Doctor is an unseen as of now member of Team Nefarious, and the team's residential scientist alongside the other doctors in the team. He is also the other main villain in Epic Mickey. The Mad Doctor is the mastermind responsible for the creation of the robotic Beetleworx that hinder Mickey's path in the cartoon wasteland. The Mad Doctor also created the robotic versions of Mickey's friends to accompany Oswald the Lucky Rabbit.
The Mad Doctor originated from the 1933 short of the the same name. In the short, he kidnaps Pluto and tries to put his head on the body of a chicken to see if it will bark, crow, or cackle. Mickey goes into the Doctor's castle to find and save Pluto. Mickey is caught and nearly killed only to realize he was dreaming. The Mad Doctor later appeared on the game Mickey Mania: The Timeless Adventures of Mickey Mouse.
He is briefly seen in a picture in the Roger Rabbit short Tummy Trouble.
The Mad Doctor served Oswald by creating Beetleworx who were meant to help out in the wasteland, and also created animatronic versions of Mickey's friends for Oswald. However, when the Shadow Blot appeared, the Doctor went over to his side. While in service to the Blot, the Doctor created evil Beetleworx designed to attack anything that opposed them. He resides at Dark Beauty Castle, and works behind the scenes after that until the encounter with him at Lonesome Manor.
He is one of the game's main villains, and like most of the antagonists in the game, is trying to escape wasteland by removing Mickey's heart. In the game, after you've fought him in Lonesome Manor, it turns out that he was a Beetleworx. Apparently, the Mad Doctor found out about the Blot's plan to drain the Wasteland of its Paint and, knowing that only the animatronics could exist if that happened, modified himself so that he could rule whatever remained as their king. However, Gus took the last rocket part from his pod, causing it to malfunction and send the Mad Doctor high into the sky, presumably never to return.
Like the Shadow Blot, the Mad Doctor is not fought directly. To defeat the Doctor, Mickey must either destroy the Beetleworx generators, or reassemble the tracks in the attic. In order to increase the amount of Thinner you have, you must destroy the generators that are creating various Beetleworx that are trying to attack you. To do this, you must use Thinner on the red lights above the doors that generate Beetleworx. If you wish to raise the amount of Paint you have, you must rescue the gremlin in the Library and the one in the Ballroom, they'll destroy two generators for you, then put a TV on the power trigger and some anvils on some buttons to lower the tracks found in the attic can be reassembled, and the cart on the track can crash into the machine behind the Mad Doctor. Either strategy will also earn Mickey the Mad Doctor Pin.
"Talk about your one-hit wonders. The Mad Doctor made his single appearance as the titular villain in the 1933 Cartoon "The Mad Doctor". And even then, he was dismissed as being a simple nightmare conjured up by a sleeping Mickey Mouse. Well, this nightmare is all too real, but even Oswald would admit that the real-life Doc seems pretty benign in comparison. Using his masterful skills in cartoon technical design, the Mad Doctor cooked up the Beetleworx, mechanical helpers who aided him in fixing and beautifying Wasteland. If he's got an evil side, he's sure doing a good job of hiding it. Maybe...too good..."
The Mad Doctor is a character in the Epic Mickey: Tales of Wasteland digicomics. These comics are a prequel to Epic Mickey and take place before the Thinner Disaster. He appears in all the comics except "One Scary Night". He's very cunning, manipulative and quite the brilliant inventor. He pretends to be friends with Oswald and to help the people of Wasteland with his ideas and inventions, but clearly has his own agenda. Ortensia seems to be one of the few that doubt his "good" intensions.
Role in the series
After his defeat, Dr. Nefarious managed to find the Mad Doctor, give him an artificial heart, helped him escape the Wasteland, and then recruited him into Team Nefarious as his only price for his help. He has not yet appeared to challenge Spongebob or Spyro, but it's unconfirmed when he will appear.